一、基本信息

姓名：钱育强

职称：助理研究员

所在部门：生物技术系

电话：18843008262

二、学习与工作经历

2015.09 - 2019.06 吉林大学 动物科学专业 农学学士学位

2019.09 - 2024.06 吉林大学 生物学专业  理学博士学位

2024.07 - 至今  吉林大学 动物科学学院 鼎新学者

三、主要科研工作

主要研究领域为基因编辑器的优化及其动物模型创制和生物育种的应用。

四、科研成果

1.Qian Y, Zhao D, Sui T, Chen M, Liu Z, Liu H, Zhang T, Chen S, Lai L, Li Z. Efficient and precise generation of Tay-Sachs disease model in rabbit by prime editing system. Cell Discov. 2021 Jul 6;7(1):50.

2. Qian Y, Wang D, Niu W, Zhao D, Li J, Liu Z, Gao X, Han Y, Lai L, Li Z. A new compact adenine base editor generated through deletion of HNH and REC2 domain of SpCas9. BMC Biol. 2023 Jul 11;21(1):155.

3. Qian Y, Wang D, Niu W, Shi Z, Wu M, Zhao D, Li J, Gao X, Zhang Z, Lai L, Li Z. Development of a highly efficient prime editor system in mice and rabbits. Cell Mol Life Sci. 2023 Nov 4;80(11):346.

4. Zhao D, Qian Y, Li J, Li Z, Lai L. Highly efficient A-to-G base editing by ABE8.17 in rabbits. Mol Ther Nucleic Acids. 2022 Jan 28;27:1156-1163.

5. Chen M, Sui T, Yang L, Qian Y, Liu Z, Liu Y, Wang G, Lai L, Li Z. Live imaging of RNA and RNA splicing in mammalian cells via the dcas13a-SunTag-BiFC system. Biosens Bioelectron. 2022 May 15;204:114074.

6. Li J, Zhao D, Zhang T, Xiong H, Hu M, Liu H, Zhao F, Sun X, Fan P, Qian Y, Wang D, Lai L, Sui T, Li Z. Precise large-fragment deletions in mammalian cells and mice generated by dCas9-controlled CRISPR/Cas3. Sci Adv. 2024 Mar 15;10(11):eadk8052.

7. Liu J, Wang Y, Tian M, Xia M, Zheng Y, Hao M, Qian Y, Shu H, Zhang W, Peng P, Zhao Z, Dong K, Peng W, Gao T, Li Z, Jin X, Wei M, Feng Y. O-GlcNAcylation of ATP-citrate lyase couples glucose supply to lipogenesis for rapid tumor cell proliferation. Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e2402674121.