一、基本信息:
于浩,男,1977年8月出生,汉族。吉林大学动物科学学院教授,博士生导师,德国法兰克福大学访问学者。主要从事《生物信息学》、《生物统计学》、《生物数学》、《转基因动物》、《动物胚胎工程》等课程的教学工作。为中国畜牧兽医学会动物遗传标记分会理事,吉林省转基因安全委员会委员,吉林大学吉林市研究院特聘专家。现为《International Journal Of Biological Macromolecules》、《Molecular Biology Reports》、《Molecular Genetics and Genomics》、《Pakistan Journal of Zoology》等杂志的审稿人。共指导毕业的硕士研究生13人,博士研究生3人。主编教材3部,参编教材1部。迄今累积发表文章100余篇,SCI收录77篇,其中以责任作者发表SCI论文40篇。获得国家授权专利1项,地方专利4项,省级科技进步二等奖1项,畜牧局一等奖2项,林业厅一等奖1项,优秀教材二等奖1项。目前,主要从事生物信息学,功能基因组学,群体遗传学等相关领域的研究。参与国家重点研发计划-《干细胞及转化研究-神经退行性疾病猪模型的建立》,现主持吉林省重点科技攻关项目一项《猪用高效绿色霉菌毒素降解剂的研究与开发》。
研究方向:
猪饲料中霉菌毒素污染的防治与绿色添加剂的开发;
猪的经济性状(肌肉发育与脂代谢)相关的分子标记的筛选鉴定;
基于高通量数据(NGS)挖掘肿瘤特异性药物靶点;
基于虚拟筛选技术开发设计新型抗氧化药物。
电子邮箱:yu_hao@jlu.edu.cn
二、学习与工作经历
1.受教育经历
1997.09-2001.07 东北农业大学生命科学学院 生物技术专业 理学学士
2001.09-2004.07 东北农业大学动物科技学院 遗传育种专业 农学硕士
2004.09-2007.07 东北农业大学动物科技学院 遗传育种专业 农学博士
2.工作经历
2007.07 - 2009.09 吉林大学畜牧兽医学院生物技术系 讲师
2009.09 - 2018.09 吉林大学动物科学学院生物技术系 副教授,硕士生导师
2018.09 - 2020.01 吉林大学动物科学学院生物技术系 副教授,博士生导师
2020.01 - 至 今 吉林大学动物科学学院生物技术系 教 授,博士生导师
三、留学经历
2022.09 - 2023.09 德国法兰克福大学(Johann Wolfgang Goethe-Universität Frankfurt am Main)访问学者
四、主要教学工作(主要承担本科生、研究生课程)
本科生课程:生物信息学、生物信息学综合分析。
研究生课程:生物信息学、生物信息学理论与实践
五、科研成果 (专著、专利 、论文)
(一)专著
1. 2017年 生物信息学综合分析 吉林大学出版社 主编
2. 2011年 生物信息学实验技术 吉林大学出版社 主编
3. 2011年 高级生物化学实验技术 科学出版社 副主编
4. 2010年 高级生物化学实验技术 吉林大学出版社 参编
(二)论文 (2016-2024)
责任作者:
1. Li, J., Pang, D., Zhou, L., Ouyang, H., Tian, Y., & Yu, H. (2024). miR-26a-5p inhibits the proliferation of psoriasis-like keratinocytes in vitro and in vivo by dual interference with the CDC6/CCNE1 axis. Aging (Albany NY), 16(5), 4631. (通讯:2区;IF=5.2)
2. Li, F., Yu, H., Qi, A., Zhang, T., Huo, Y., Tu, Q., ... & **e, Z. (2024). Regulatory Non-Coding RNAs during Porcine Viral Infections: Potential Targets for Antiviral Therapy. Viruses, 16(1), 118. (并列一作:2区;IF=4.7)
3. Wang R, Yu H, Chen P, et al. Integrated transcriptome and molecular docking to identify the hub superimposed attenuation targets of curcumin in breast cancer cells[J]. International Journal of Molecular Sciences, 2023, 24(15): 12479. (并列一作:2区;IF=5.6)
4. Chen, S., Liu, Z., Yu, H., Lai, L., & Li, Z. (2022). Efficient multi-nucleotide deletions using deaminase-Cas9 fusions in human cells. Journal of Genetics and Genomics. (并列一作:1区;IF=5.723)
5. Zhai, Y., Yu, H., An, X. et al. Profiling the transcriptomic signatures and identifying the patterns of zygotic genome activation – a comparative analysis between early porcine embryos and their counterparts in other three mammalian species. BMC Genomics 23, 772 (2022). https://doi.org/10.1186/s12864-022-09015-4(并列一作:2区;IF=4.547)
6. Jiao, Y., Hao, L., Xia, P., Cheng, Y., Song, J., Chen, X., ... & Yu, H. (2022). Identification of Potential miRNA–mRNA Regulatory Network Associated with Pig Growth Performance in the Pituitaries of Bama Minipigs and Landrace Pigs. Animals, 12(21), 3058. (通讯:2区;IF=3.231)
7. Guan S, Zhong L, Yu H, et al. Molecular Docking and Proteomics Revealed the Synergistic Antibacterial Mechanism of Theaflavin with βlactam Antibiotics Against MRSA[J]. Frontiers in Microbiology, 4299. (通讯:2区;IF=6.064)
8. Shi, L., Zhai, Y., Zhao, Y., Kong, X., Zhang, D., Yu, H., & Li, Z. (2022). ELF4 is critical to zygotic gene activation and epigenetic reprogramming during early embryonic development in pigs. Frontiers in Veterinary Science, 9. (通讯:2区;IF=3.471)
9. Yuan, D.; Yu, H.; Liu, S.; Hao, L.; Zhang, J. Prediction and Experimental Verification of a Hierarchical Transcription Factor Regulatory Network of Porcine Myoglobin (Mb). Animals 2021, 11, 3599. https://doi.org/10.3390/ani11123599(并列一作:2区;IF=2.752)
10. Z Zhou Y, Zhang J, Li W, Zhang D, Wang Z, Zhai Y, Yu H, Li Z. Integrative investigation of the TF-miRNA coregulatory network involved in the inhibition of breast cancer cell proliferation by resveratrol. FEBS Open Bio. 2021 Dec 2. doi: 10.1002/2211-5463.13344. Epub ahead of print. PMID: 34856073. (通讯:4区;IF=2.693)
11. Zhang Jing*, Wang Rui, Li Ruihua, Yu Hao and Fang Hengtong, “Review of the biological activity of maslinic acid1”, Current Drug Targets (2021) 22: 1. (通讯:3区;IF=3.465)
12. Li, R.; Fang, H.; Shen, J.; Jin, Y.; Zhao, Y.; Wang, R.; Fu, Y.; Tian, Y.; Yu, H.; Zhang, J. Curcumin Alleviates LPS-Induced Oxidative Stress, Inflammation and Apoptosis in Bovine Mammary Epithelial Cells via the NFE2L2 Signaling Pathway. Toxins 2021, 13, 208. https://doi.org/10.3390/toxins13030208 (通讯:2区;IF=4.546)
13. Daoyu Zhang, Xinglan An, Hao Yu, Ziyi Li; The regulatory effect of 6-TG on lncRNA-miRNA-mRNA ceRNA network in triple-negative breast cancer cell line. Biosci Rep 2021; BSR20203890. doi: https://doi.org/10.1042/BSR20203890 (通讯:3区;IF=3.84)
14. Li, H., An, X., Li, Q., Yu, H., & Li, Z. (2021). Construction and analysis of competing endogenous RNA network of MCF‑7 breast cancer cells based on the inhibitory effect of 6‑thioguanine on cell proliferation. Oncology Letters, 21, 104. https://doi.org/10.3892/ol.2020.12365 (通讯:4区;IF=2.967)
15. Ruihua Li, Jing Zhang, Yongfeng Zhou, Qi Gao, Rui Wang, Yurong Fu, Lianwen Zheng, Hao Yu, "Transcriptome Investigation and In Vitro Verification of Curcumin-Induced HO-1 as a Feature of Ferroptosis in Breast Cancer Cells", Oxidative Medicine and Cellular Longevity, vol. 2020, Article ID 3469840, 18 pages, 2020. (通讯:2区;IF=6.543)
16. Zhang D, An X, Li Q, Man X, Chu M, Li H, Zhang N, Dai X, Yu H and Li Z (2020) Thioguanine Induces Apoptosis in Triple-Negative Breast Cancer by Regulating PI3K – AKT Pathway. Front. Oncol. 10:524922. doi: 10.3389/fonc.2020.524922 (通讯:2区;IF=6.244)
17. Chen, Siyu & Xie, Wanhua & Liu, Zhiquan & Shan, Huanhuan & Chen, Mao & Song, Yuning & Yu, Hao & Lai, Liangxue & li, Zhanjun. (2020). CRISPR Start-Loss: A novel and practical alternative for gene silencing through base-editing-induced start codon mutations. Molecular Therapy - Nucleic Acids. 10.1016/j.omtn.2020.07.037. (通讯:2区;IF=8.886)
18. Chen, S. , Jia, Y. , Liu, Z. , Shan, H. , Chen, M. , & Yu, H. , et al. (0). Robustly improved base editing efficiency of cpf1 base editor using optimized cytidine deaminases. Cell Discovery. (通讯:2区;IF=10.849)
19. Jing Zhang, Xin Wang, Yun Zhao, Yongcheng Jin, Yongfeng Zhou, Junmei Wang, Yurong Fu, Rui Wang, Ruihua Li, Hengtong Fang and Hao Yu (2020). Changes of Colon Flora and Antitoxic Effect Induced by Zearalenone in Mice. Pakistan J. Zool., Vol. 52, Iss. 4, pp 1555-1562. (通讯:4区;IF=0.831)
20. Rui Wang, Hao Yu, Hengtong Fang, Yongcheng Jin, Yun Zhao, Jinglin Shen, Changhai Zhou, Ruihua Li, Junmei Wang, Yurong Fu & Jing Zhang Effects of dietary grape pomace on the intestinal microbiota and growth performance of weaned piglets[J]. Archives of animal nutrition, 2020:1-13. (并列一作:2区;IF=2.242)
21. Li, H., An, X., Zhang, D., Li, Q., Zhang, N., Yu, H., & Li, Z. (2020). Transcriptomics Analysis of the Tumor-Inhibitory Pathways of 6-Thioguanine in MCF-7 Cells via Silencing DNMT1 Activity. OncoTargets and Therapy, 13, 1211-1223. (通讯:3区;IF=4.147)
22. Chaogang Yao, Daxin Pang, Chao Lu, Aishi Xu, Peixuan Huang, Hongsheng Ouyang and Hao Yu (2020). Investigation on the Effect of Two Fat Metabolism Related Pathways on Intramuscular Fat Content in Pigs. Pakistan J. Zool., pp 1-14, 2021. DOI: 10.17582/journal.pjz/20190407110454 (通讯:4区;IF=0.831)
23. Wang J, Yu H, Yili A, Gao Y, Hao L, Aisa HA, Liu S. Identification of hub genes and potential molecular mechanisms of chickpea isoflavones on MCF-7 breast cancer cells by integrated bioinformatics analysis. Ann Transl Med 2019. doi: 10.21037/atm.2019.12.141(并列一作:2区;IF=3.297)
24. Li, Q., An, X., Man, X., Chu, M., Zhao, T., Yu, H., & Li, Z. (2019). Transcriptome analysis reveals that cyclophosphamide induces premature ovarian failure by blocking cholesterol biosynthesis pathway. Life sciences, 239, 116999. (通讯:3区;IF=3.647)
25. Geng, H., Hao, L., Cheng, Y., Wang, C., Huang, S., Wei, W., Yu, H & Lu, H. (2019). Interaction between CA repeat microsatellites and HIF1α regulated the transcriptional activity of porcine IGF1 promoter. Journal of applied genetics, 1-8. (通讯:4区;IF=2.027)
26. Jiang, Y., An, X. L., Yu, H., Cai, N. N., Zhai, Y. H., Li, Q., ... & Zhang, X. M. Transcriptome profile of bovine iPSCs derived from Sertoli Cells. Theriogenology Jiang Y , An X L , Yu H , et al. Transcriptome profile of bovine iPSCs derived from Sertoli Cells[J]. Theriogenology, 2019, 146. (并列一作:2区;IF=2.094)
27. Wang, X., Yu, H., Fang, H., Zhao, Y., Jin, Y., Shen, J., ... & Zhang, J. (2019). Transcriptional profiling of zearalenone-induced inhibition of IPEC-J2 cell proliferation. Toxicon, 172, 8-14. (并列一作:2区;IF=2.201)
28. Yao, C., Pang, D., Lu, C., Xu, A., Huang, P., Ouyang, H., & Yu, H. (2019). Data Mining and Validation of AMPK Pathway as a Novel Candidate Role Affecting Intramuscular Fat Content in Pigs. Animals, 9(4), 137. (通讯:2区;IF=2.323)
29. Peixuan Huang, Daxin Pang, Kankan Wang, Aishi Xu, Chaogang Yao, Mengjing Li, Wenni You, Qiushuang Wang, and Hao Yu. The Possible Role of Complete Loss of Myostatin in Limiting Excessive Proliferation of Muscle Cells (C2C12) via Activation of MicroRNAs [J]. International journal of molecular sciences, 2019, 20(3), 643. (通讯:2区;IF=4.556)
30. Xin Wang, Hao Yu, Anshan Shan, Yongcheng Jin, Hengtong Fang, Yun Zhao, Jinglin Shen, Changhai Zhou, Yongfeng Zhou, Yurong Fu, Junmei Wang & JingZhang Toxic effects of Zearalenone on intestinal microflora and intestinal mucosal immunity in mice[J]. Food and Agricultural Immunology, 2018, 29(1): 1002—1011. (并列一作:2区;IF=2.398)
31. Yunyun Cheng, Songcai Liu,GangWang, Wenzhen Wei,ShanHuang, RuiYang, Hongwei Geng,Haoyang Li, JieSong, Lidan Sun, HaoYu, LinlinHao. Porcine IGF1 synonymous mutation alter gene expression and protein binding affinity with IGF1R.[J]. International Journal of Biological Macromolecules, 2018, 116. (通讯:2区;IF= 4.784)
32. Qingyan Wu, Hao Yu, Wenzhen Wei, Yunyun Cheng, Shan Huang, Hongyu Shi, Songcai Liu, Jichao Xia, Hongyao Jia, Linlin Hao. Linkage disequilibrium and functional analysis of PRE1 insertion together with SNPs in the promoter region of IGFBP7 gene in different pig breeds.[J]. Journal of Applied Genetics, 2018, 59(2):231. (并列一作:4区;IF= 1.725)
33. Zhang Z, Zhai Y., Ma X, Zhang S, An X, Yu H, Li Z. Down-Regulation of H3K4me3 by MM-102 Facilitates Epigenetic Reprogramming of Porcine Somatic Cell Nuclear Transfer Embryos[J]. Cellular Physiology & Biochemistry, 2018, 45(4):1529-1540. (通讯:2区;IF= 5.5)
34. XiaodiZhang, ZhichenKang, QingjieLid, JinZhang, ShaCheng, HaoChang, ShanshanWang, ShufangCao, TieLifJi, weiLi, YishanWang, YuSong, HaoYu. Antigen-adjuvant effects of icariin in enhancing tumor-specific immunity in mastocytoma-bearing DBA/2J mice,Biomedicine & Pharmacotherapy,Volume 99,2018,Pages 810-816, (通讯:3区;IF= 3.743)
35. Wang G, Hao L, Cheng Y, Li S, Zhang Y, Lv C, Wei W, Huang S, Shi H, Dong L, Zhang Y, Yu H, Zhang J. Effects of GnRHR polymorphisms on sperm quality in Chinese water buffalo[J]. Animal Reproduction Science, 2017, 186. (通讯:2区;IF= 1.647)
36. Cheng Y, Liu S, Su D, Lu C, Zhang X, Wu Q, Li S, Fu H, Yu H, Hao L Distribution and linkage disequilibrium analysis of polymorphisms of GH1 gene in different populations of pigs associated with body size.[J]. Journal of Genetics, 2016, 95(1):79-87. (通讯:4区;IF= 0.672)
37. Qingyan Wu, Hao Yu, Xibi Fang, Yunyun Cheng, Lijie Dong, Wenzhen Wei, Gang Wang, Haoyu Fu, Songcai Liu & Linlin Hao. The association of haplotypes in IGFBP-3 gene promoter region and tissue expressions in three pig breeds[J]. Animal Cells & Systems the Official Publication of the Zoological Society of Korea, 2016, 20(6):1-10. (并列一作:4区;IF= 0.97)
38. C. Lu, H. Yu, Y. Xing, Y.-Y. Cheng, Q.-Y. Wu, S.-M. Li, H.-Y. Fu, X. Zhang, L.-L. Hao & D. Liu Haplotype diversity in MC1R locus between the Min and white-haired pig breeds[J]. Acta Agriculturae Scandinavica, 2017:1-6. (并列一作:4区;IF= 0.631)
39. Jing Zhang, Guochao Wu, Anshan Shan, Yu Han, Yongcheng Jin, Hengtong Fang, Yun Zhao, Jinglin Shen, Changhai Zhou, Chunjin Li, Lu Chen, Yongfeng Zhou, Xin Wang, Di Liu & Hao Yu. Dietary glutamine supplementation enhances expression of ZO-1 and occludin and promotes intestinal development in Min piglets[J]. Acta Agriculturae Scandinavica, 2017:1-7. (通讯:4区;IF= 0.631)
40. Hao L L, Yu H, Zhang Y, et al. Single nucleotide polymorphism analysis of exons 3 and 4 of IGF-1 gene in pigs[J]. Genet Mol Res, 2011, 10: 1689-1695. (并列一作:4区;IF= 0.85)
合作作者:
41. Wang, C., Fu, Y., Wang, R., Wang, Q., Yu, H., & Zhang, J. (2023). Quercetin Attenuates the Combined Effects of Zearalenone and Lipopolysaccharide on IPEC-J2 Cell Injury through Activating the Nrf2 Signaling Pathway. Toxins, 15(12), 679.
42. Tian, Y., Che, H., Yang, J., **, Y., Yu, H., Wang, C., ... & Zhang, J. (2023). Astaxanthin Alleviates Aflatoxin B1-Induced Oxidative Stress and Apoptosis in IPEC-J2 Cells via the Nrf2 Signaling Pathway. Toxins, 15(3), 232.
43. Chen, S., Liu, Z., Xie, W., Yu, H., Lai, L., & Li, Z. (2022). Compact Cje3Cas9 for efficient in vivo genome editing and adenine base editing. The CRISPR Journal, 5(3), 472-486.
44. Liu, Z., Chen, S., Xie, W., Yu, H., Lai, L., & Li, Z. (2022). Versatile and efficient genome editing with Neisseria cinerea Cas9. Communications biology, 5(1), 1-7.
45. Fu, Y., Jin, Y., Tian, Y., Yu, H., Wang, R., Qi, H., ... & Zhang, J. (2022). Zearalenone Promotes LPS-Induced Oxidative Stress, Endoplasmic Reticulum Stress, and Accelerates Bovine Mammary Epithelial Cell Apoptosis. International Journal of Molecular Sciences, 23(18), 10925.
46. Deng, J., Yang, L., Wang, Z., Ouyang, H., Yu, H., Yuan, H., & Pang, D. (2022). Advance of genetically modified pigs in xeno-transplantation. Frontiers in Cell and Developmental Biology, 10.
47. Ren, Z., Fang, H., Zhang, J., Wang, R., Xiao, W., Zheng, K., Hao Yu & Zhao, Y. (2022). Dietary Aronia melanocarpa Pomace Supplementation Enhances the Expression of ZO-1 and Occludin and Promotes Intestinal Development in Pigs. Frontiers in Veterinary Science, 9.
48. Zhou, Lin, Jianing Li, Jinsong Liu, Anbei Wang, Ying Liu, Hao Yu, Hongsheng Ouyang, and Daxin Pang. 2021. "Investigation of the lncRNA THOR in Mice Highlights the Importance of Noncoding RNAs in Mammalian Male Reproduction" Biomedicines 9, no. 8: 859. https://doi.org/10.3390/biomedicines9080859
49. Yang XQ, Zhao XL, Yu H, et al. Speckled 100 kDa gene in pigs: Alternative splicing, subcellular localization, and response to interferon-α stimulation. Gene. 2021 May;791:145710. DOI: 10.1016/j.gene.2021.145710.
50. Zhai Y, Zhang M, An XL, Zhang S, Kong X, Li Q, Yu H, Dai XP, Li Z. TRIM28 maintains genome imprints and regulates development of porcine SCNT embryos. Reproduction (Cambridge, England). PMID 33539314 DOI: 10.1530/REP-20-0602
51. Fu Y, Jin Y, Shan A, Zhang J, Tang H, Shen J, Zhou C, Yu H, Fang H, Zhao Y, Wang J, Tian Y. Polydatin Protects Bovine Mammary Epithelial Cells Against Zearalenone-Induced Apoptosis By Inhibiting Oxidative Responses and Endoplasmic Reticulum Stress. Toxins (Basel). 2021 Feb 5;13(2):121. doi: 10.3390/toxins13020121. PMID: 33562867.
52. Zhai Y, Zhang M, An XL, Zhang S, Kong X, Li Q, Yu H, Dai XP, Li Z. TRIM28 maintains genome imprints and regulates development of porcine SCNT embryos. Reproduction. 2021 Feb 1:REP-20-0602.R2. doi: 10.1530/REP-20-0602. Epub ahead of print. PMID: 33539314.
53. Sui L, Huang R, Yu H, et al. Inhibition of HDAC6 by tubastatin A disrupts mouse oocyte meiosis via regulating histone modifications and mRNA expression[J]. Journal of Cellular Physiology, 2020
54. Yao, L., Wang, H., Song, Y., Dai, Z., Yu, H., Yin, M., ... & Zhao, Y. (2019). Large-scale prediction of ADAR-mediated effective human A-to-I RNA editing. Briefings in Bioinformatics, 20(1), 102-109.
55. Wei, Wenzhen; Wang, Gang; Cheng, Yunyun; Yang, Rui; Song, Jie; Huang, Shan; Li, Haoyang; Geng, Hongwei; Yu, Hao; Liu, Songcai; Hao, Linlin, A miR-511-binding site SNP in the 3UTR of IGF-1 gene is associated with proliferation and apoptosis of PK-15 cells, In Vitro Cellular & Developmental Biology-Animal, 2019, 55(5): 323-330.
56. Wang, Junmei; Jin, Yongcheng; Wu, Shunlu; Yu, Hao; Zhao, Yun; Fang, Hengtong; Shen, Jinglin; Zhou, Changhai; Fu, Yurong; Li, Ruihua; Wang, Rui; Wang, Junxiong; Zheng, Kexin; Fan, Qingsong; Chen, Bojiong; Zhang, Jing, Deoxynivalenol induces oxidative stress, inflammatory response and apoptosis in bovine mammary epithelial cells, Journal of Animal Physiology and Animal Nutrition, 2019, 103(6): 1663-1674.
57. Zhou, Yongfeng; Jin, Yongcheng; Yu, Hao; Shan, Anshan; Shen, Jinglin; Zhou, Changhai; Zhao, Yun; Fang, Hengtong; Wang, Xin; Wang, Junmei; Fu, Yurong; Wang, Rui; Li, Ruihua; Zhang, Jing, Resveratrol inhibits aflatoxin B1-induced oxidative stress and apoptosis in bovine mammary epithelial cells and is involved the Nrf2 signaling pathway, Toxicon, 2019, 164: 10-15.
58. Yunyun Cheng, Songcai Liu, Gang Wang, Wenzhen Wei, Shan Huang, Rui Yang, Hongwei Geng, Haoyang Li, Jie Song, Lidan Sun, Hao Yu, Linlin Hao (2018). Porcine IGF1 synonymous mutation alter gene expression and protein binding affinity with IGF1R. International Journal of Biological Macromolecules,, 23-30.
59. Wang H, An X, Yu H. MiR-29b/TET1/ZEB2 signaling axis regulates metastatic properties and epithelial-mesenchymal transition in breast cancer cells:[J]. Oncotarget, 2017, 8(60):102119-102133.
60. Cheng Yunyun; Gu Jiaming; Xue Han; Li Qiang; Liang Mingming; Wang Nan; Wang Gang; Wu Qingyan; Liu Songcai; Yu Hao; Zhang Jiabao; Hao Linlin, Identification of Four SNPs in LHB Gene and Their Associations with Sperm Qualities of Chinese Buffaloes, Animal Biotechnology, 2017, 28(3): 168-173.
61. Yunyun Cheng, Songcai Liu, Xin Zhang, Qingyan Wu, Siming Li, Haoyu Fu, Lijie Dong, Hao Yu, Linlin Hao. (2016). Expression Profiles of IGF-1R Gene and Polymorphisms of its Regulatory Regions in Different Pig Breeds.. Protein Journal, 35(3), 231-236.
62. Yunyun Cheng, Songcai Liu, Chao Lu, Qingyan Wu, Siming Li, Haoyu Fu, Gang Wang, Chen Lv, Linyan Nie, Yu Zhang, Hao Yu, Linlin Hao. (2016). Missense mutations in the signal peptide of the porcine GH gene affect cellular synthesis and secretion. Pituitary, 19(4), 362-369.
63. Yunyun Cheng, Songcai Liu, Ying Zhang, Dan Su, Gang Wang, Chen L, Yu Zhang, Hao Yu, Linlin Hao. (2016). The effect of heat stress on bull sperm quality and related HSPs expression. Animal Biology,, 321-333.
64. Xiao, H., Zhao, Z., Fang, X., Yu, H., Long, X., Jiang, P., & Yang, R. (2016). ASSOCIATION OF THE ACSL5 GENE G.33185918G > A AND G.33186348C > T MUTATIONS WITH CARCASS AND MEAT QUALITY TRAITS OF CHINESE SIMMENTAL-CROSS STEERS. Journal of Animal and Plant Sciences, 26(3), 658-664.
65. Su Dan; Hao Linlin; Chen Fuwang; Li Siming; Abdelrahman Ahmed Mohamed; Zhang Yu; Yu Hao; Liu Songcai; Li Mingtang, CspE is Overproduced by Temperature Downshift in the Acinetobacter johnsonii DBP-3, Current Microbiology, 2016, 72(5): 563-569.
66. Wang Nan; Liu Songcai; Shi Hui; Zhang Peng; Cheng Yunyun; Su Dan; Lu Chao; Yu Hao; Hao Linlin, Prokaryotic-expressed porcine IFN alpha 1-THY alpha 1 fusion proteins exert IFN and THY activities in vitro, Biologicals, 2015, 43(4): 225-231.
67. Wang, Nan & Liu, Songcai & Shi, Hui & Zhang, Peng & Cheng, Yunyun & Su, Dan & Lu, Chao & Yu, Hao & Hao, Linlin. (2015). Prokaryotic-expressed porcine IFNα1-THYα1 fusion proteins exert IFN and THY activities in vitro. Biologicals. 43. 10.1016/j.biologicals.2015.05.007.
68. Xibi Fang, Songcai Liu, Yunyun Cheng, Siming Li, Qingyan Wu, Dan Su, Chao Lu, Hao Yu, Linlin Hao (2015). SNPs in the 5' terminal-region of IGFBP6 gene and its linkage with pig body size. Animal Cells and Systems, 19(6), 417-424.
69. Fang, X. B., Liu, S., Wu, Q. Y., Li, S. M., Cheng, Y. Y., Fu, H. Y., ... & Hao, L. L. (2015). Linkage analysis of SNPs in IGFBP-6 and its relation with the body sizes of pig.. Genetics and Molecular Research, 14(4), 17273-17280.
70. Yang Wang, Yuan Lv, Jiachang Cai, Stefan Schwarz, Lanqing Cui, Zhidong Hu, Rong Zhang, Jun Li, Qin Zhao, Tao He, Dacheng Wang, Zheng Wang, Yingbo Shen, Yun Li, Andrea T Fesler, Congming Wu, Hao Yu, Xuming Deng, Xi Xia, Jianzhong Shen. (2015). A novel gene, optrA, that confers transferable resistance to oxazolidinones and phenicols and its presence in Enterococcus faecalis and Enterococcus faecium of human and animal origin. Journal of Antimicrobial Chemotherapy, 70(8), 2182-2190.
71. Guan Yuan; Li Xinwei; Zhang Xin; Cheng Yunyun; Su Dan; Lu Chao; Fang Xibi; Ma Qiang; Zhang Dawei; Yu Hao; Hao Linlin; Liu Songcai, Controlled Delivery of Growth-Hormone-Releasing Peptide 6 from the acid) Copolymer and the Effect of a Growth- Hormone- Releasing Peptide 6-Copolymer Hydrogel on the Growth of Rex Rabbits, Journal of Applied Polymer Science, 2014, 131(9).
72. Huang, Y., Ouyang, H., Yu, H., Lai, L., Pang, D., & Li, Z. (2013). Efficiency of porcine somatic cell nuclear transfer – a retrospective study of factors related to embryo recipient and embryos transferred. Biology Open, 2(11), 1223-1228.
73. Liu Y, Hao L, Zhang Y, Wang J, Yu H, Liu S. Heat stress alters Hsp70 expression profiling in mouse testicular tissue[C]// 33rd Annual Meeting of the German-Society-for-Cell-Biology/German. 2010.
74. Yan, Sen; Song, Hong; Pang, Daxin; Zou, Qingjian; Li, Li; Yan, Quanmei; Fan, Nana; Zhao, Xiangjie; Yu, Hao; Li, Zhanjun; Wang, Haijun; Gao, Fei; Ouyang, Hongsheng; Lai, Liangxue, Expression of Plant Sweet Protein Brazzein in the Milk of Transgenic Mice, PLos One, 2013, 8(10): e76769.
75. Gu Jingmin; Liu Xiaohe; Yang Mei; Li Yue; Sun Changjiang; Lu Rong; Song Jun; Zhang Qingming; Lei Liancheng; Feng Xin; Du Chongtao; Yu Hao; Yang Yongjun; Han Wenyu, Genomic characterization of lytic Staphylococcus aureus phage GH15: providing new clues to intron shift in phages, Journal of General Virology, 2013, 94: 906-915.
76. Gu Jingmin; Liu Xiaohe; Lu Rong; Li Yue; Song Jun; Lei Liancheng; Sun Changjiang; Feng Xin; Du Chongtao; Yu Hao; Yang Yongjun; Han Wenyu, Complete Genome Sequence of Staphylococcus aureus Bacteriophage GH15, Journal of Virology, 2012, 86(16): 8914-8915.
77. Liu, H.,Guo, L. J.,Liu, D., Zhai, C. Y. Yu, H. Expression, characterization, and variation of the porcine calpain 7 gene.[J].Acta Agriculturae Scandinavica. Section A, Animal Science,2009,59(4):204-210.