一、基本信息
姓名：杨雨薇
职称：讲师
所在部门：动物科学系
研究方向：动物遗传育种与繁殖
办公电话：0431-87836177
电子邮件：yangyuwei@jlu.edu.cn
二、学习与工作经历
2011.09-2015.06，山西农业大学，动物科学专业，农学学士
2015.09-2018.06，吉林大学，动物遗传育种与繁殖，农学硕士
2018.09-2021.06，东北农业大学，动物遗传育种与繁殖，农学博士
2021.11-至今，吉林大学，动物科学学院，讲师
三、主要教学工作
本科生课程：《家禽生产学》；研究生课程：《表观遗传学》
四、主要科研工作（包括科研项目）
主要研究领域为非编码RNA调控机制研究。熟悉基因的作用机制和研究手段、精通细胞培养及药物作用机制研究。研究方向主要包括基于多组学技术，挖掘与解析影响畜禽繁殖性状主效基因及相关分子遗传标记；家禽肠道菌群对其生产性能的影响等。参与一项国自然基金项目。
五、科研成果（著作、专利、论文）
1. Zheng JL, Liang S, Zhang Y, Sun XQ, Li YM, Diao JZ, Dong LP, Ni HY, Yin YJ, Ren J, Yang YW, Zhang YH (2022). Effects of Compound Chinese Herbal Medicine Additive on Growth Performance and Gut Microbiota Diversity of Zi Goose. Animals (Basel). 2022 Oct 26;12(21):2942. doi: 10.3390/ani12212942. PMID: 36359068. (通讯)
2. Xie HL, Zhang YH, Tan XD, Zheng Y, Ni HY, Dong LP, Zheng JL, Diao JZ, Yin YJ, Zhang JB, Sun XQ, Yang YW (2022). miR-375 Induced the Formation and Transgenerational Inheritance of Fatty Liver in Poultry by Targeting MAP3K1. DNA Cell Biol 41(6):590-599. (通讯)
3. Zhang YH, Xie HL, Yang YW, Wen J, Liu RR, Zhao GP, Tan XD, Liu Z, Zheng Y, Zhang JB (2022). miR-375 up-regulates lipid metabolism and inhibits cell proliferation involved in chicken fatty liver formation and inheritance via targeting recombination signal binding protein for immunoglobulin kappa J region (RBPJ). Poult. Sci. 102218. https://doi.org/10.1016/j.psj.2022.102218
4. Yang CX#, Yang YW#, Mou Q, Chen L, Huo LJ, Du ZQ (2022). Global change of microRNA expression induced by vitamin C treatment on immature boar Sertoli cells. Theriogenology 183:1-9. (共一)
5. Yang CX#, Yang YW#, Mou Q, Chen L, Wang C, Du ZQ (2022). Proteomic changes induced by ascorbic acid treatment on porcine immature Sertoli cells. Theriogenology 188:13-21. (共一)
6. Mou Q, Yang YW, Chen L, Fang T, Yao YC, Du ZQ, Yang CX (2022). Melatonin mitigates Chloroquine-induced defects in porcine immature Sertoli cells. Theriogenology 177:1-10.
7. Ni H#, Zhang Y#, Yang Y, Li Y, Yin Y, Sun X, Xie H, Zheng J, Dong L, Diao J, Sun H, Zhang Y, Liang S (2022) Comparative Analyses of Production Performance, Meat Quality, and Gut Microbial Composition between Two Chinese Goose Breeds. Animals (Basel) 12(14).
8. Yang CX, Chen L, Yang YW, Mou Q, Du ZQ (2021). Acute heat stress reduces viability but increases lactate secretion of porcine immature Sertoli cells through transcriptome reprogramming. Theriogenology 173:183-192.
9. Yang YW, Chen L, Mou Q, Liang H, Du ZQ, Yang CX (2020). Ascorbic acid promotes the reproductive function of porcine immature Sertoli cells through transcriptome reprogramming. Theriogenology 158:309-320.
10. Yang, YW., Chen, L., Yang, CX (2019). Heat Shock Protein 90 and Reproduction in Female Animals: Ovary, Oocyte and Early Embryo. In: Asea, A., Kaur, P. (eds) Heat Shock Protein 90 in Human Diseases and Disorders. Heat Shock Proteins, vol 19. Springer, Cham. https://doi.org/10.1007/978-3-030-23158-3_23.
11. Li X, Jiang P, Yu H, Yang Y, Xia L, Yang R, Fang X, Zhao Z (2019). miR-21-3p Targets Elovl5 and Regulates Triglyceride Production in Mammary Epithelial Cells of Cow. DNA Cell Biol 38(4):352-357.
12. Yang Y, Fang X, Yang R, Yu H, Jiang P, Sun B, Zhao Z (2018). MiR-152 Regulates Apoptosis and Triglyceride Production in MECs via Targeting ACAA2 and HSD17B12 Genes. Sci Rep 8(1):417.
13. Guo J, Liu X, Yang Y, Liang M, Bai C, Zhao Z, Sun B (2018). miR-375 down-regulation of the rearranged L-myc fusion and hypoxia-induced gene domain protein 1A genes and effects on Sertoli cell proliferation. Asian-Australas J Anim Sci 31(8):1103-1109.
14. Liu X, Yang Y, Jiang P, Li X, Ge Y, Cao Y, Zhao Z, Fang X, Yu X (2018). Effect of QSOX1 on cattle carcass traits as well as apoptosis and triglyceride production in bovine fetal fibroblasts and mammary epithelial cells. J Vet Med Sci 80(8):1329-1336.
15. Shen B, Pan Q, Yang Y, Gao Y, Liu X, Li W, Han Y, Yuan X, Qu Y, Zhao Z (2017). miR-224 Affects Mammary Epithelial Cell Apoptosis and Triglyceride Production by Downregulating ACADM and ALDH2 Genes. DNA Cell Biol 36(1):26-33.
16. Gao Y, Qin L, Yang Y, Dong X, Zhao Z, Zhang G, Zhao Z (2017). PDPN gene promotes the proliferation of immature Bovine Sertoli cells in vitro. Anim Reprod Sci 179:35-43.
17. Fang X, Zhao Z, Yu H, Li G, Jiang P, Yang Y, Yang R, Yu X (2017). Comparative genome-wide methylation analysis of longissimus dorsi muscles between Japanese black (Wagyu) and Chinese Red Steppes cattle. PLoS One 12(8):e0182492.
18. Liu, X., Guo, J., Zhou, M., Yang, Y., Liang, M., Bai, C., Zhao, Z., & Sun, B (2017). RNA binding protein QKI contributes to WT1 mRNA and suppresses apoptosis in ST cells. Genes & Genomics, 39, 967-974.
19. Yang Y, Pan Q, Sun B, Yang R, Fang X, Liu X, Yu X, Zhao Z (2016). miR-29b Targets LPL and TDG Genes and Regulates Apoptosis and Triglyceride Production in MECs. DNA Cell Biol 35(12):758-765.
20. 杨雨薇,房希碧,于海滨,姜平,杨润军,赵志辉. 奶牛乳腺上皮细胞中Bta-miR-877靶基因的初步验证[J]. 中国兽医学报, 2018, 38(04):809-813.
21.潘琪琪,杨雨薇,高岩,韩云胜,袁雪,刘鑫,赵志辉,沈冰蕾,曲永利. 奶牛乳腺上皮细胞中miR-224靶基因的初步验证[J]. 中国兽医学报,2017,37(01):112-117.
22.赵志辉，闫守庆，郭鹏程，杨冬雪，刘鑫，杨雨薇. 一种预示牛奶中体细胞数的分子检测试剂盒. CN205821334U.
